Ovary-Sparing Radiation Planning Techniques Can Achieve Ovarian Dose Reduction for Soft Tissue Sarcoma of the Buttock and Thigh

Table 4

Univariate and multivariate analysis of likelihood of reduction in mean bilateral ovary dose (MBOD) with an ovary-sparing plan.

	Reduction in; MBOD	No reduction; in MBOD	UVA; value	MVA; value
Mean distance to pubic symphysis (cm) (95% CI)	6.3; (4.5, 8.1)	14.1; (8.2, 19.9)		0.0038^∧
Site, number (%)
Proximal medial thigh	10 (77%)	3 (23%)
Buttock	3 (75%)	1 (25%)
Other thigh	1 (17%)	5 (83%)		0.048^∧
Largest GTV dimension (cc) (95% CI)	8.7; (5.6, 11.8)	9.5; (6.0, 13.0)		0.054^∧

MBOD: mean bilateral ovary dose; SD: standard deviation; UVA: univariate analysis; MVA: multivariate analysis; cm: centimeter; cc: cubic centimeter. -test value. Fisher’s exact value. ^∧Logistic regression chi-square value.