Preoperative Factors Associated with Infiltrative Histologic Growth Patterns in Extremity Soft Tissue Sarcoma

Table 3

Preoperative factors associated with histological growth pattern.

Factors	Univariate			Multivariate
	OR	95% CI	value	OR	95% CI	value
Age	1.01	1.00–1.03	0.14
Gender			0.80
Female	1.00
Male	0.80	0.41–1.55
Preoperative radiation therapy			1.00
Done	1.00
Not done	1.00
Preoperative chemotherapy			0.49
Done	1.59	0.43–5.90
Not done	1.00
Depth
Superficial	3.00	1.09–8.22
Deep	1.00
Size	1.00	0.95–1.05	0.91
Compartmental status			0.51
Intracompartmental	1.00
Extracompartmental	1.25	0.63–2.46
Previous treatment			0.20
Fresh	1.00
Recurred	2.18	0.84–5.65
Unplanned excision	1.66	0.64–4.29
Peritumoral edema			0.65
Absent	1.00
Present	0.84	0.40–1.76
Tumor border on MRI
Pushing	1.00			1.00
Infiltrative	2.62	1.31–5.23		2.48	1.21–5.08
FNCLCC grade			0.83
1	1.00
2	1.30	0.49–3.47
3	1.34	0.52–3.48
Liposarcoma
Liposarcoma	1.00			1.00
Others	5.38	1.47–19.63		4.57	1.22–17.05

OR, odds ratio; CI, confidence interval; statistically significant.