Clinical Study

Predictors of Wound Complications following Radiation and Surgical Resection of Soft Tissue Sarcomas

Table 1

Patient and tumor characteristics.

CharacteristicMajor wound complicationAny wound complication
YesNoYesNo

Sex0.950.55
 Female7 (50%)27 (51%)10 (45%)24 (53%)
 Male7 (50%)26 (49%)12 (55%)21 (47%)
Age62.2 (19.5)57.0 (16.3)0.1962.8 (17.7)55.7 (16.3)0.08
Obese (BMI ≥ 30)0.750.08
 Yes5 (36%)16 (30%)10 (45%)11 (24%)
 No9 (64%)37 (70%)12 (55%)34 (76%)
Diabetes mellitus0.050.01
 Yes4 (29%)4 (8%)6 (27%)2 (4%)
 No10 (71%)49 (92%)16 (73%)43 (96%)
Tobacco use0.690.65
 Current or past smoker5 (36%)22 (42%)14 (64%)26 (58%)
 Never smoker9 (64%)31 (58%)8 (36%)19 (42%)
Tumor location1.00.24
 Upper extremity2 (14%)8 (15%)5 (23%)5 (11%)
 Lower extremity12 (86%)42 (79%)17 (77%)37 (82%)
 Trunk0 (0%)3 (6%)0 (0%)3 (7%)
Tumor location in extremity0.740.77
 Proximal11 (79%)36 (68%)17 (77%)30 (67%)
 Distal3 (21%)14 (26%)5 (23%)12 (27%)
 Trunk0 (0%)3 (6%)0 (0%)3 (6%)
Tumor depth relative to fascia0.830.09
 Deep8 (57%)32 (60%)10 (45%)30 (67%)
 Superficial6 (43%)21 (40%)12 (55%)15 (33%)
Resected specimen size (cm)13.0 (13.7)11.9 (13.1)0.6512.9 (8.7)13.3 (6.4)0.31
Tumor size (cm) 11.1 (9.6)7.9 (4.7)0.6010.1 (7.6)7.8 (5.0)0.49

Continuous variables are reported as mean (SD). Categorical variables are reported as (%). Total count values may not sum to 67 due to missing data. Bolded values correspond to covariates that met a level of significance of for inclusion in the multivariable model. BMI: body mass index. cm: centimeter.