Research Article
Pasteurized Autograft-Prosthesis Composite Reconstruction May Not Be a Viable Primary Procedure for Large Skeletal Defects after Resection of Sarcoma
| Characteristics | Number of patients (%) |
| Age | | ≤14, >40 | 50 (35.2) | 15–40 | 92 (64.8) | Average 24 years (4–72) | | Gender | | Male | 90 (63.3) | Female | 52 (36.7) | Pathologic diagnosis | | Osteosarcoma | 112 (78.9) | Chondrosarcoma | 15 (10.6) | Ewing’s sarcoma | 5 (3.5) | Metastatic carcinoma | 3 (2.1) | MFH, bone | 2 (1.4) | | 5 (3.5) | Initial tumor volume (cc) | | ≤200 ml | 100 (70.4) | >200 ml | 42 (29.6) | Average | 186.2 | Location | | Femur | | Proximal | 26 (18.3) | Distal | 44 (30.9) | Total | 6 (4.2) | Pelvis | 15 (10.6) | Humerus | | Proximal | 10 (7.1) | Total | 2 (1.4) | Tibia | | Proximal | 39 (27.5) | Pasteurization length (cm) | | ≤10 cm | 36 (25.4) | >10 cm | 106 (74.6) | Fixation modality | | Cemented | 127 (89.4) | Cementless | 15 (10.6) | Local recurrence | | Proximal femur | 5 (3.5) | Distal femur | 3 (2.1) | Proximal tibia | 4 (2.8) | Metastasis | 51 (36) | Final status | | Continuous disease-free | 86 (60.6) | No evidence of disease | 15 (10.6) | Died of disease | 39 (27.4) | Alive with disease | 2 (1.4) | Follow-up | | Average 110 months (21–278) | |
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Each case of giant cell tumor, rhabdomyosarcoma, synovial sarcoma, hemangioendothelioma, and desmoplastic fibroma.
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