Research Article

Pasteurized Autograft-Prosthesis Composite Reconstruction May Not Be a Viable Primary Procedure for Large Skeletal Defects after Resection of Sarcoma

Table 1

Patients demographics .

CharacteristicsNumber of patients (%)

Age
 ≤14, >4050 (35.2)
 15–40 92 (64.8)
 Average 24 years (4–72)
Gender
 Male90 (63.3)
 Female52 (36.7)
Pathologic diagnosis
 Osteosarcoma112 (78.9)
 Chondrosarcoma15 (10.6)
 Ewing’s sarcoma5 (3.5)
 Metastatic carcinoma3 (2.1)
 MFH, bone2 (1.4)
5 (3.5)
Initial tumor volume (cc)
 ≤200 ml100 (70.4)
 >200 ml42 (29.6)
 Average186.2
Location
 Femur
  Proximal26 (18.3)
  Distal44 (30.9)
  Total6 (4.2)
 Pelvis15 (10.6)
 Humerus
  Proximal10 (7.1)
  Total2 (1.4)
 Tibia
  Proximal39 (27.5)
Pasteurization length (cm)
 ≤10 cm36 (25.4)
 >10 cm106 (74.6)
Fixation modality
 Cemented127 (89.4)
 Cementless15 (10.6)
Local recurrence
 Proximal femur5 (3.5)
 Distal femur3 (2.1)
 Proximal tibia4 (2.8)
Metastasis51 (36)
Final status
 Continuous disease-free86 (60.6)
 No evidence of disease15 (10.6)
 Died of disease39 (27.4)
 Alive with disease2 (1.4)
Follow-up
 Average 110 months (21–278)

Each case of giant cell tumor, rhabdomyosarcoma, synovial sarcoma, hemangioendothelioma, and desmoplastic fibroma.