The Value of MRI in Distinguishing Subtypes of Lipomatous Extremity Tumors Needs Reassessment in the Era of MDM2 and CDK4 Testing

Figure 2

(a) Axial T1 MR of left shoulder with 12 cm lipomatous tumor. Formula and expert observers predicted benign lipoma, while initial pathology was concerning ALT/WDL. Lack of MDM2 amplification with FISH confirmed a diagnosis of benign lipoma. (b) Axial T1 MR of the left arm with 2 cm lipomatous tumor. Formula and expert observers predicted benign lipoma, which was later confirmed by lack of MDM2 amplification through FISH after initial pathology was concerning ALT/WDL.

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