The Value of MRI in Distinguishing Subtypes of Lipomatous Extremity Tumors Needs Reassessment in the Era of MDM2 and CDK4 Testing

Figure 3

(a) Coronal T1 and (b) axial STIR MR images of the right thigh lipomatous tumor. Expert observers interpreted the lesion as heterogeneous, containing stranding, and having foci of high T2 signal. All four readers interpreted the tumor as ALT/WDL in addition to initial pathology interpreted as ALT/WDL. MDM2 amplification during FISH analysis confirmed benign lipoma on two separate occasions, illustrating the variability that can be seen within simple lipomas.

(a)

(b)