Review Article
High-Dose Chemotherapy with Stem Cell Rescue in Desmoplastic Small Round Cell Tumor: A Single-Institution Experience and Review of the Literature
Table 2
Demographics of patients with desmoplastic small round cell tumor treated at Children’s Hospital at Montefiore and in literature review.
| All patients | | |
| Median age at diagnosis | 18.3 years | | Overall survival | 3 years, 36% | 5 years, 13% |
| Category | | Percentage | Female | 34 | 13 | Male | 220 | 86 | Unknown | 2 | 1 |
| Primary abdominal/pelvic disease | 198 | 77 | Primary nonabdominal disease | 24 | 9 | Unknown | 34 | 13 |
| Liver metastasis | 126 | 49 | No liver metastasis | 54 | 21 | Unknown | 76 | 30 |
| Extra-abdominal metastasis | 62 | 24 | No extra-abdominal metastasis | 142 | 55 | Unknown | 52 | 20 |
| SCT | 71 | 28 | SCT not in remission | 23 | | SCT in remission | 13 | | SCT unknown remission | 35 | | No SCT | 185 | 72 |
| Radiation | 86 | 34 | No radiation | 167 | 65 | Unknown | 3 | 1 |
| HiPEC | 16 | 6 | No HiPEC | 202 | 79 | Unknown | 38 | 15 |
| Doxorubicin | 130 | 51 | No doxorubicin | 15 | 6 | Unknown | 111 | 43 |
| Alkylating agent | 134 | 52 | Alkylating-like agent | 8 | 3 | No alkyating agent | 3 | 1 | Unknown | 111 | 43 |
| 0 treatment | 9 | 4 | 1 treatment | 52 | 20 | 2 treatments | 87 | 34 | 3 treatments | 65 | 25 | 4–5 treatments | 38 | 15 | Unknown | 4 | 2 |
| Complete surgical excision (2,3,4) | 56 | 22 | Incomplete surgical excision (0,1) | 39 | 15 | Unknown | 161 | 63 |
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SCT: stem cell transplant; HiPEC: hyperthermic intraperitoneal chemotherapy.
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