Research Article
The Volume-Outcome Relationship in Retroperitoneal Soft Tissue Sarcoma: Evidence of Improved Short- and Long-Term Outcomes at High-Volume Institutions
Table 5
Cox regression model for overall survival: all patients.
| Variable | 95% Wald | Odds ratio | Confidence limits | value |
| Age | 1.02 | 1.02 | 1.03 | <0.0001 |
| Female (reference = male) | 0.79 | 0.72 | 0.87 | <0.0001 |
| Race (reference = white) | | Black | 0.81 | 0.69 | 0.96 | 0.015 | Other | 0.88 | 0.71 | 1.09 | 0.23 |
| Insurance (reference = private) | | Medicaid | 1.38 | 1.11 | 1.70 | 0.0034 | Medicare | 1.14 | 1.00 | 1.30 | 0.056 | No insured | 1.38 | 1.07 | 1.79 | 0.014 | Other government | 1.18 | 0.75 | 1.86 | 0.47 | Unknown | 1.23 | 0.85 | 1.78 | 0.28 |
| No high school degree (reference ≥ 29%) | | <14% | 0.77 | 0.67 | 0.90 | 0.0007 | 14–19.9% | 0.86 | 0.73 | 1.00 | 0.055 | 20–28.9% | 0.92 | 0.79 | 1.08 | 0.30 |
| Charlson–Deyo (reference = 2) | | 0 | 0.72 | 0.58 | 0.88 | 0.0011 | 1 | 0.81 | 0.65 | 1.01 | 0.055 |
| Tumor size (reference = <5 cm) | | 5–10 cm | 1.02 | 0.83 | 1.25 | 0.85 | >10 cm | 1.43 | 1.19 | 1.73 | 0.0001 |
| Grade (reference = grade 3) | | Grade 1 | 0.34 | 0.28 | 0.40 | <0.0001 | Grade 2 | 0.52 | 0.44 | 0.61 | <0.0001 | Unknown | 0.64 | 0.56 | 0.73 | <0.0001 |
| Margins (reference = R0) | | R1 | 1.31 | 1.15 | 1.49 | <0.0001 | R2 | 2.18 | 1.73 | 2.75 | <0.0001 | Unknown | 1.61 | 1.44 | 1.80 | <0.0001 |
| Surgery (reference = yes) | | No | 0.93 | 0.83 | 1.04 | 0.21 |
| Radiation (reference = yes) | | No | 0.80 | 0.72 | 0.90 | <0.0001 |
| Chemotherapy (reference = yes) | | No | 1.26 | 1.11 | 1.42 | 0.0004 |
| Hospital volume (reference = high) | | Medium | 1.44 | 0.98 | 2.10 | 0.064 | Low | 1.57 | 1.16 | 2.11 | 0.0032 |
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