Research Article

Using the Spleen as an In Vivo Systemic Immune Barometer Alongside Osteosarcoma Disease Progression and Immunotherapy with α-PD-L1

Table 3

Non-WBC cell PD-L1 expression of primary tumors isolated from BALB/c mice inoculated with TF (n = 15) or WT (n = 11) K7M2 cells.

MarkerWT % expressionTF % expressionp

PD-L11.96 ± 0.77%1.91 ± 1.28%0.9

Statistical significance was assessed using a two–tailed Student’s T-test and 95% confidence. WBC = white blood cell; PD-L1 = programmed death-ligand 1; TF = transfected; WT = wild-type.