Outcome for Advanced or Metastatic Soft Tissue Sarcoma of Nonextremities Treated with Doxorubicin-Based Chemotherapy: A Retrospective Study from a Single Cancer Institution
Table 1
The baseline characteristics of the patients treated with the doxorubicin-based chemotherapy.
No. (%)
Sex
Male
40 (53)
Female
35 (46)
Age
Median age, years
55 (21–75)
ECOG performance status
0
57 (76)
1
15 (20)
2
3 (4)
Location of the primary tumor
Head and neck
14 (19)
Thorax
7 (9)
Abdomen
23 (31)
Retroperitoneum
19 (25)
Genital organs
4 (5)
Others
4 (5)
Unknown
4 (5)
Number of involved organs
1
22 (29)
2
26 (35)
3
13 (17)
4
10 (13)
≧5
4 (5)
Site of involved organs, no. (%)
Head and neck
11 (15)
Intra-abdomen
30 (40)
Retroperitoneum
15 (20)
Lung
35 (47)
Liver
22 (29)
Bone
18 (24)
Lymph node
16 (21)
Others
29 (39)
Maximum length
Median (cm)
5.3 (0–21.7)
>5 cm
40 (53)
Pretreatment
Operation
49 (65)
Radiation
21 (28)
Chemotherapy
8 (11)
None
18 (24)
Histopathology type
Leiomyosarcoma
17 (23)
Liposarcoma
15 (20)
Spindle cell sarcoma, NOS
14 (19)
Pleomorphic sarcoma
6 (8)
Synovial sarcoma
5 (7)
Others
18 (24)
Others include angiosarcoma, undifferentiated pleomorphic sarcoma, solitary fibrous tumor, low-grade fibromyxoid sarcoma, malignant peripheral nerve sheath tumor, breast phyllodes tumor, round cell sarcoma with CIC rearrangement, neuroblastoma, malignant extrarenal rhabdoid tumor, and myxofibrosarcoma.
