Clinical Study

Targeting Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors (MPNST) in a Phase II Study of Everolimus in Combination with Bevacizumab (SARC016)

Table 2

Tumor response evaluation based on the WHO and RECIST criteria (stage 1: 15 patients; stage 2: 10 patients).

Response evaluationStage 1Stage 2
Cycle 2 (N = 15)Cycle 4 (N = 8)Cycle 2 (N = 10)Cycle 4 (N = 5)

WHO
 Partial response1000
 Stable disease7152
 Progressive disease5543
 Others2210
RECIST
 Partial response0000
 Stable disease9254
 Progressive disease4441
 Others2210

Partial response was unconfirmed and thus not counted as clinical benefit.