Time Trends and Prognostic Factors for Overall Survival in Myxoid Liposarcomas: A Population-Based Study
Table 1
Baseline characteristics of patients with localized and metastatic disease at diagnosis.
Characteristics
Localized disease
Metastatic disease
Total
p value
Total patients (n = )
851
50
901
Median follow-up (years)(IQR)
8.3 [2.8–15.8]
0.8 [0.5–1.9]
7.6 [2.4–15.3]
0.000
Gender
N.S
Male
480 (56%)
32 (64%)
512 (57%)
Female
371 (44%)
18 (36%)
389 (43%)
Tumor location
N.S.
Upper limb
51 (6%)
2 (4%)
53 (6%)
Lower limb
551 (65%)
26 (52%)
577 (64%)
Trunk
170 (20%)
15 (30%)
185 (21%)
Other
79 (9%)
7 (14%)
86 (9%)
Tumor grade
N.S.
Intermediate grade (MLS)
779 (92%)
45 (90%)
824 (91%)
High grade (RC tumor)
72 (8%)
5 (10%)
77 (9%)
Age (years)
0.004
<40
238 (28%)
8 (16%)
352 (39%)
40–55
304 (36%)
16 (32%)
312 (35%)
56–70
204 (25%)
16 (32%)
169 (19%)
>70
105 (12%)
10 (20%)
68 (7%)
TNM classification
0.000
pT0
12 (1%)
1 (2%)
13 (1%)
pT1
173 (20%)
0
173 (19%)
pT2
502 (59%)
18 (36%)
520 (58%)
pTx
164 (19%)
31 (62%)
195 (22%)
cN0
569 (67%)
21 (42%)
590 (66%)
cN1
2 (0%)
5 (10%)
7 (1%)
cNx
280 (33%)
24 (48%)
304 (34%)
cM0
648 (76%)
0
648 (72%)
cM1
0
50 (100%)
50 (6%)
cMx
203 (24%)
0
203 (23%)
Surgical resection
0.000
Radical (R0)
368 (43%)
4 (8%)
372 (41%)
Microscopic irradical(R1)
57 (7%)
2 (4%)
59 (7%)
Macroscopic irradical (R2)
15 (2%)
7 (14%)
22 (2%)
Unknown status (Rx)
366 (43%)
8 (15%)
374 (42%)
No surgery
45 (5%)
29 (58%)
74 (8%)
Other treatments
0.000
Radiotherapy (RT)
452 (53%)
14 (28%)
466 (52%)
Chemotherapy
50 (6%)
19 (38%)
69 (8%)
The P value represents outcome of Chi-square statistical testing (or the Student's t-test in case of an continuous variable). Abbreviations: pT = pathological T-stage, cN = clinical nodal stage, cM = clinical metastasis stage, N.S. = not significant.
