Research Article

Time to Treatment Initiation and Survival in Adult Localized High-Grade Bone Sarcoma

Table 1

Demographic data.

FactorTotal (N = 2,122)

Time to treatment initiation, days (IQR)25.0 [12.0, 42.0]
Age
 18–30654 (30.8%)
 31–50555 (26.2%)
 51–70627 (29.5%)
 71+286 (13.5%)
Sex
 Male1,241 (58.5%)
 Female881 (41.5%)
Race
 White1,735 (81.8%)
 Black258 (12.2%)
 Other/unknown129 (6.1%)
Charlson/Deyo score
 01,843 (86.9%)
 1222 (10.5%)
 ≥257 (2.7%)
Histology
 Osteosarcoma1,217 (57.4%)
 Chondrosarcoma486 (22.9%)
 Ewing’s sarcoma195 (9.2%)
 Chordoma17 (0.80%)
 Other207 (9.8%)
Facility type
 Comm. cancer prg.38 (1.8%)
 Comprehensive comm. cancer prg.286 (13.5%)
 Academic center856 (40.3%)
 Integrated network cancer prg.62 (2.9%)
 Other/unknown880 (41.5%)
Insurance
 Uninsured120 (5.7%)
 Private insurance1,148 (54.1%)
 Medicaid258 (12.2%)
 Medicare454 (21.4%)
 Other/unknown142 (6.7%)
Income
 <$38,000404 (19.0%)
 $38,000-$47,999500 (23.6%)
 $48,000-$62,999563 (26.5%)
 $63,000+655 (30.9%)
Distance from facility
 <21 miles974 (45.9%)
 21–50 miles466 (22.0%)
 51–100 miles306 (14.4%)
 >100 miles376 (17.7%)
Transition in care
 No1,137 (53.6%)
 Yes985 (46.4%)
Year of diagnosis
 2004160 (7.5%)
 2005213 (10.0%)
 2006226 (10.7%)
 2007202 (9.5%)
 2008244 (11.5%)
 2009273 (12.9%)
 2010274 (12.9%)
 2011267 (12.6%)
 2012263 (12.4%)
Primary tumor site
 Upper extremity281 (13.2%)
 Lower extremity985 (46.4%)
 Pelvis344 (16.2%)
 Other512 (24.1%)
Tumor size
 ≤8.0 cm967 (45.6%)
 >8.0 cm1,155 (54.4%)
Grade
 Poorly differentiated1,253 (59.0%)
 Undifferentiated869 (41.0%)
Clinical staging
 Stage I239 (11.3%)
 Stage II1,782 (84.0%)
 Stage III101 (4.8%)
First-line treatment modality
 Surgery1,029 (48.5%)
 Radiation86 (4.1%)
 Systemic994 (46.8%)
 Multimodal13 (0.61%)
Vital status
 Died922 (43.4%)
 Alive1,200 (56.6%)

Statistics presented as median [P25, P75] or N (column %). Community cancer program: between 100 and 500 new cancer cases annually, Comprehensive community cancer program: >500 new cancer cases annually, academic center: >500 new cancer cases annually and resident/medical education, integrated network: multiple facilities providing comprehensive services with a unified cancer committee. comm., community; prg., program.