Research Article

Predictors of Recurrence and Patterns of Initial Failure in Localized Ewing Sarcoma: A Contemporary 20-Year Experience

Table 2

Patterns of failure and sites of first recurrence in patients with recurrence of initially localized or metastatic Ewing sarcoma.

LocalizedMetastatic

Number of patients2134

Metastatic site(s) at time of diagnosisLung only11 (32%)
Lung + other10 (29%)
Bone only4 (12%)
All other9 (26%)

Pattern of first failureLocal4 (19%)1 (8%)
Distant14 (67%)12 (54%)
Both3 (14%)7 (38%)

Postrecurrence site(s) of distant metastasesLung only9 (53%)4 (21%)
Lung + other5 (29%)5 (26%)
Bone only2 (12%)4 (21%)
All other1 (6%)6 (32%)