Bone Metastases in Patients with Leiomyosarcoma: A Retrospective Analysis of Survival and Surgical Management

Table 4

Cox regression analysis of survival in 396 patients with leiomyosarcoma.

Variable	Hazard ratio (95% CI)	P
Presence of bone metastases	1.0 (0.67–1.5)	0.97
Primary LMS^†
Bone	0.35 (0.10–1.1)	0.08
Extremity soft tissue	0.46 (0.29–0.72)	0.001
Dermal	0.21 (0.06–0.66)	0.008
Uterine	0.93 (066–1.3)	0.70
Peritoneal	1.5 (0.55–4.2)	0.41
Lung	2.2 (0.55–9.2)	0.26
Breast	0.72 (0.10–5.2)	0.75
Gynecologic	0.29 (0.07–1.2)	0.08
Male reproductive	0.33 (0,12–0.91)	0.03
Gastrointestinal	0.84 (0.26–2.7)	0.77
Inferior vena cava	0.91 (0.28–2.9)	0.87
Liver	2.8 (1.0–7.8)	0.05
H&N	0.27 (0.04–2.0)	0.20
Mediastinal	0.63 (0.09–4.6)	0.65
Unknown	7.0 (2.1–23.6)	0.002

^†Retroperitoneal; statistically significant ().