Recent Developments in the Surgical Treatment of Bone Tumors and Their Impact on Quality of Life

Publishing date
30 Aug 2013
Submission deadline
12 Apr 2013

Lead Editor

1Klinikum rechts der Isar, Technische Universität München, Munich, Germany

2Istituto Ortopedico Rizzoli, Università di Bologna, Bologna, Italy

3Surgery, Radiology & Orthopedics Senior Research Fellow NDORMS University of Oxford, UK

Recent Developments in the Surgical Treatment of Bone Tumors and Their Impact on Quality of Life


Treatment of malignant bone tumors often consists of both chemotherapy and/or radiation, as well as surgery. Since surgical techniques are rapidly improving, for example, with the advancement of the so-called limb salvage surgery and its promising functional results, ablative procedures retreat more and more into the background. Due to the application of modern therapy in combination with limb-sparing surgery, the number of long-term survivors increased dramatically within the last decades especially in patients with nonmetastatic bone tumors. Therefore, the consideration of health-related quality of life becomes increasingly significant besides the development of innovative and gentle surgical methods and reconstruction techniques.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to develop new and gentle surgical techniques and innovative reconstruction methods, improve health-related quality of life, and implement psycho-oncological screenings and treatment. We are particularly interested in articles describing new resection methods as well as modern prosthesis designs (including coatings); the use of navigation for tumor resection and its impact on margins and functional results; the long-term outcome after rotationplasty and expandable endoprosthesis with respect to quality of life; new implant generations of expandable tumor prostheses; survival of allografts and extracorporeally treated bone segments; long-term outcome of biologic reconstruction and possible complications; new applications of biological reconstructions; oncologic and functional outcome after epiphyseal preservation; long-term limb preservation and secondary amputation; new concepts for palliation and their impact on quality of life.

All articles should place increased emphasis on health-related quality of life as well as psycho-oncological aspects of bone tumors. Potential topics include, but are not limited to:

  • Quality of life after different surgical treatments
  • Role of psycho-oncology in treatment of cancer patients
  • Expandable prostheses versus rotationplasty
  • Recent concepts in limb salvage surgery
  • Long-term survival after limb salvage and its impact on quality of life
  • Navigation and computer-guided tumor surgery
  • Reconstruction after resection of pelvic tumors
  • Recent developments in limb sparing surgery including photodynamic surgery and radiodynamic surgery
  • Improvements in implant design (including coatings) and their effect on long-term survival

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2013
  • - Article ID 826432
  • - Editorial

Recent Developments in the Surgical Treatment of Bone Tumors and Their Impact on Quality of Life

Andreas F. Mavrogenis | Ulrich Lenze | ... | Pietro Ruggieri
  • Special Issue
  • - Volume 2013
  • - Article ID 505321
  • - Clinical Study

Dedifferentiated Peripheral Chondrosarcoma: A Review of Radiologic Characteristics

Eric R. Henderson | Elisa Pala | ... | Pietro Ruggieri
  • Special Issue
  • - Volume 2013
  • - Article ID 767960
  • - Research Article

Do Malignant Bone Tumors of the Foot Have a Different Biological Behavior than Sarcomas at Other Skeletal Sites?

M. Brotzmann | F. Hefti | ... | A. H. Krieg
  • Special Issue
  • - Volume 2013
  • - Article ID 787653
  • - Clinical Study

Surgical Guides (Patient-Specific Instruments) for Pediatric Tibial Bone Sarcoma Resection and Allograft Reconstruction

Laura Bellanova | Laurent Paul | Pierre-Louis Docquier
  • Special Issue
  • - Volume 2013
  • - Article ID 153640
  • - Review Article

Can Bone Tissue Engineering Contribute to Therapy Concepts after Resection of Musculoskeletal Sarcoma?

Boris Michael Holzapfel | Mohit Prashant Chhaya | ... | Dietmar Werner Hutmacher
  • Special Issue
  • - Volume 2012
  • - Article ID 197540
  • - Research Article

Comparison of Surface Area across the Allograft-Host Junction Site Using Conventional and Navigated Osteotomy Technique

Ajay Lall | Eric Hohn | ... | David S. Geller
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