In Silico Characterization and Homology Modeling of a Cyanobacterial Phosphoenolpyruvate Carboxykinase Enzyme

Figure 1

Multiple sequence alignment of selected regions of ATP- and GTP-dependent PEPCKs. The yellow block highlights are amino acid stretches that are conserved and exclusive to cyanobacterial PEPCKs; the amino acids in the blue blocks make up the pyruvate binding site; the kinase-1a and kinase 2 motifs are highlighted by the red and pink boxes, respectively; the active site lid amino acids are shaded in green; the adenine binding site is highlighted in olive green. The alignment was generated with Clustal W [5].