Clinical Study
The Neural Correlates of Mental Rotation Abilities in Cannabis-Abusing Patients with Schizophrenia: An fMRI Study
Table 3
ROI activations during the mental rotation task (experimental relative to control condition) in the 3 groups (1-sample student’s
-test).
| Brain region | R/L | MNI coordinates | Z-score | Voxels | value | | | |
| Control group | | | | | | | | Inferior parietal | L | −35 | −42 | 46 | 5.30 | 120 | 0.001 | Supramarginal | R | 38 | −35 | 42 | 5.14 | 86 | 0.001 | Superior parietal | L | −24 | −60 | 63 | 4.97 | 169 | 0.001 | Precentral | L | −28 | −14 | 49 | 4.32 | 36 | 0.003 | Superior frontal | L | −24 | −7 | 63 | 4.00 | 43 | 0.003 | Precentral | R | 32 | −7 | 56 | 4.30 | 80 | 0.001 | SCZ group | | | | | | | | Thalamus | L | −7 | −4 | 10 | 3.37 | 31 | 0.050 | DD group | | | | | | | | Superior parietal | L | −18 | −63 | 49 | 3.97 | 198 | 0.002 | Supplementary motor area | R | 14 | 4 | 70 | 3.71 | 17 | 0.013 | Precentral | L | −35 | −10 | 46 | 3.64 | 27 | 0.012 | Inferior parietal | L | −38 | −35 | 38 | 3.45 | 27 | 0.010 | Supramarginal | L | −49 | −38 | 28 | 3.42 | 19 | 0.018 | R | 56 | −28 | 52 | 3.21 | 15 | 0.036 | Superior parietal | R | 21 | −56 | 56 | 3.44 | 43 | 0.008 |
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R: right; L: left; is FDR corrected at 0.05.
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