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Schizophrenia Research and Treatment
Volume 2017, Article ID 6120970, 8 pages
Research Article

Impact of Pharmacist Counselling on Clozapine Knowledge

1Pharmacy Department, St. Patrick’s University Hospital, James St., Dublin 8, Ireland
2Pharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cavanagh Pharmacy Building, Cork, Ireland
3Department of Pharmacy, Mercy University Hospital, Grenville Place, Cork, Ireland

Correspondence should be addressed to Ciara Ní Dhubhlaing; moc.liamstapts@gnialhbuhdinc

Received 25 January 2017; Revised 4 May 2017; Accepted 16 May 2017; Published 13 June 2017

Academic Editor: Luis San

Copyright © 2017 Ciara Ní Dhubhlaing et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Clozapine is the only antipsychotic with evidence for efficacy in treatment of resistant schizophrenia but it carries a high side effect burden. Patient information is provided but may be poorly retained. This study aims to examine the impact of pharmacist counselling upon patient knowledge of clozapine. Outpatients, aged 18 years and over, attending St. Patrick’s University Hospital, Dublin, participated in this study between June and August 2015. The intervention consisted of pharmacist counselling on two occasions one month apart. Knowledge was assessed using a 28-point checklist devised from the currently available clozapine patient information sources, at baseline and after each counselling session. Ethics approval was obtained. Twenty-five participants (40% female; mean age 45.1 years, SD 9.82; 64% unemployed, 28% smokers) showed an improvement in knowledge scores of clozapine from baseline to postcounselling on each occasion with an overall improvement in knowledge score, from baseline to postcounselling at one month, of 39.43%; . This study adds to the evidence that interventions involving pharmacist counselling can improve patient knowledge, whilst the specific knowledge gained relating to recognition of side effects may help patients towards more empowerment regarding their treatment.