| Females only |
| Males only | Placebo | 45.39 (26.02, 64.96) | 83.93 (51.04, 117.00) | 21.06 (7.11, 34.99) | 19.41 (0.83, 37.88) | −1.47 (−22.03, 19.02) | 17.83 (−1.72, 37.39) | 20.09 (−2.59, 43.13) | 19.07 (7.38, 30.93) | Risperidone 1–3 mg/day | 38.41 (3.66, 73.84) | −24.38 (−48.30, −0.35) | −26.03 (−52.87, 1.00) | −46.86 (−75.20, −18.82) | −27.58 (−55.01, −0.15) | −25.30 (−55.39, 4.43) | 29.46 (17.20, 41.73) | 10.36 (−2.01, 22.94) | Risperidone 4–6 mg/day | −62.85 (−98.96, −27.00) | −64.48 (−102.70, −26.72) | −85.25 (−124.90, −46.32) | −66.09 (−104.50, −27.90) | −63.70 (−103.40, −24.08) | −2.70 (−8.97, 3.59) | −21.83 (−35.26, −8.46) | −32.17 (−46.08, −18.40) | Quetiapine 400 mg/day | −1.69 (−17.11, 13.71) | −22.52 (−47.18, 2.14) | −3.20 (−27.30, 20.91) | −0.90 (−27.88, 25.88) | 2.81 (−2.95, 8.54) | −16.27 (−29.36, −3.18) | −26.65 (−40.29, −13.13) | 5.54 (−0.04, 11.05) | Quetiapine 800 mg/day | −20.80 (−48.43, 6.66) | −1.48 (−28.68, 25.29) | 0.67 (−28.60, 29.87) | 3.04 (−4.82, 10.87) | −16.05 (−30.30, −2.08) | −26.43 (−41.22, −11.94) | 5.71 (−4.30, 15.74) | 0.23 (−9.52, 9.86) | Paliperidone 1.5 mg/day | 19.32 (−7.47, 45.84) | 21.50 (−7.73, 50.80) | 22.18 (10.88, 33.43) | 3.04 (−13.14, 19.30) | −7.33 (−23.97, 9.28) | 24.87 (11.96, 37.86) | 19.35 (6.66, 31.87) | 19.16 (6.50, 31.75) | Paliperidone 3–6 mg/day | 2.32 (−25.95, 31.03) | 20.61 (9.40, 32.00) | 1.54 (−14.70, 17.62) | −8.87 (−25.30, 7.58) | 23.35 (10.46, 36.24) | 17.82 (5.19, 30.41) | 17.59 (4.98, 30.30) | −1.52 (−16.40, 13.56) | Paliperidone 6–12 mg/day |
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