Polygenic Risk Scores for Subtyping of Schizophrenia

Table 3

Change of cognitive functions between baseline and Visit 6.

	Mean Diff	-value	df	95% CI	value
VIGILANCE
All subjects	−0.30	−5.31	200	−0.40–−0.19	3.0E-07
Class I	−0.23	−2.64	79	−0.40–−0.06	0.0099
Class II	−0.24	−1.45	33	−0.59–0.10	0.1578
Class III	−0.41	−2.97	24	−0.70–−0.13	0.0066
Class IV	−0.34	−2.41	23	−0.63–−0.05	0.0242
Class V	−0.38	−3.03	37	−0.63–−0.13	0.0045
PROCESSING SPEED
All subjects	−0.24	−6.45	224	−0.32–−0.17	6.8E-10
Class I	−0.20	−3.56	87	−0.31–−0.09	0.0006
Class II	−0.29	−2.85	38	−0.50–−0.08	0.0071
Class III	−0.29	−2.41	27	−0.54–−0.04	0.0229
Class IV	−0.26	−2.17	26	−0.51–−0.01	0.0395
Class V	−0.25	−3.23	42	−0.40–−0.09	0.0024
WORKING MEMORY
All subjects	−0.20	−4.27	224	−0.29–−0.11	2.8E-05
Class I	−0.21	−3.14	87	−0.34–−0.08	0.0023
Class II	−0.18	−1.36	38	−0.44–0.09	0.1819
Class III	−0.09	−0.57	27	−0.44–0.25	0.5740
Class IV	−0.26	−2.12	26	−0.52–−0.01	0.0433
Class V	−0.21	−2.32	42	−0.39–−0.03	0.0252
REASONING
All subjects	−0.27	−5.15	224	−0.38–−0.17	5.8E-07
Class I	−0.28	−3.27	87	−0.45–−0.11	0.0015
Class II	−0.24	−1.95	38	−0.50–0.01	0.0585
Class III	−0.27	−1.67	27	−0.60–0.06	0.1056
Class IV	−0.40	−2.78	26	−0.69–−0.10	0.0100
Class V	−0.20	−1.66	42	−0.44–0.04	0.1053

Mean Diff: mean difference between the baseline and Visit 6; 95% CI: 95% confident interval; -value: Test value; df: Degree of freedom; values ≤0.05 were highlighted in bold.