Increasing Prevalence of Unique Mutation Patterns in H5N1 Avian Influenza Virus HA and NA Glycoproteins from Human Infections in Egypt

Table 1

Marker-like mutations in the hemagglutinin and neuraminidase proteins of highly pathogenic avian influenza virus H5N1 in human and poultry isolates from Egypt compared to other countries with human cases as retrieved from public data bases.

Country	Hemagglutinin			Neuraminidase
	Isolates	S/L/V129^1	$\Delta$129	Isolates	A/S/V/D46	V/L/S/F339
Vietnam	249^2	56/193/0	0	160	120/36/4/0	0/0/160/0
Indonesia	162	141/21/0	0	44	43/1/0/0	0/0/40/4
Thailand	161	1/159/1	0	70	70/0/0/0	0/0/70/0
China	475	355/120/0	0	201	145/1/55/0	0/0/199/2
Nigeria	174	172/2/0	0	34	34/0/0/0	0/0/34/0
Egypt	310	202/38/0	70	134	86/0/0/48	3/2/81/48
Total	1531	927	70	643	498/38/59/48	3/2/584/54

${}^1$ Variations of amino acid residues at the indicated position of the mature HA5 (D₁Q₂I₃ …) and the nascent NA 1(M₁N₂P₃ …).
${}^2$ Numbers of isolates in GenBank.