Research Article
Contralateral Prophylactic Mastectomy among Women with Pathogenic Variants in BRCA1/2: Overall Survival, Racial, and Ethnic Differences
Table 1
Patient characteristics by race/ethnicity (N = 144).
| | Variable | Levels | Whites, n = 114 (%) | Nonwhites, n = 30 (%) | All N = 144 (%) | value |
| | Age at diagnosis | Median, years | 40 | 39.5 | 40 | 0.36 |
| | Diagnosis year | Median | | | | |
| | Marital status | Married | 83 (72.8) | 20 (66.7) | 103 (71.5) | 0.5 | | Other | 31 (27.2) | 10 (33.3) | 41 (28.5) |
| | Education | ≥High school | 85 (81.7) | 17 (63.0) | 102 (77.9) | 0.07 | | <High school | 19 (18.3) | 10 (37.0) | 29 (22.1) |
| | Family history of breast cancer | No | 60 (53.1) | 12 (41.4) | 72 (50.7) | 0.3 | | Yes | 53 (46.9) | 17 (58.6) | 70 (49.3) |
| | Family history of ovarian cancer | No | 99 (87.6) | 24 (82.8) | 123 (86.6) | 0.54 | | Yes | 14 (12.4) | 5 (17.2) | 19 (13.4) |
| | Stage | I | 35 (30.7) | 7 (23.3) | 42 (29.2) | 0.2 | | II | 51 (44.7) | 19 (63.3) | 70 (48.6) | | III | 28 (24.6) | 4 (13.3) | 32 (22.2) |
| | Nodal status | Node 0 | 57 (50.0) | 14 (46.7) | 71 (49.3) | 0.17 | | Node 1 | 35 (30.7) | 10 (33.3) | 45 (31.2) | | Node 2 | 7 (6.1) | 5 (16.7) | 12 (8.3) | | Node 3 | 15 (13.2) | 1 (3.3) | 16 (11.1) |
| | CPM | No | 50 (43.9) | 13 (43.3) | 63 (43.8) | 0.1 | | Yes | 64 (56.1) | 17 (56.7) | 81 (56.2) |
| | HR status | ER−/PR− | 59 (52.2) | 12 (40.0) | 71 (49.6) | 0.3 | | ER+ or PR+ | 54 (47.8) | 18 (60.0) | 72 (50.4) |
| | HER2/neu status | Negative | 98 (87.5) | 27 (90.0) | 125 (88.0) | 0.1 | | Positive | 14 (12.5) | 3 (10.0) | 17 (12.0) |
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HR: hormone receptor; CPM: contralateral prophylactic mastectomy.
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