Contralateral Prophylactic Mastectomy among Women with Pathogenic Variants in BRCA1/2: Overall Survival, Racial, and Ethnic Differences

Table 2

Univariate logistic regression models for contralateral prophylactic mastectomy.

Parameter	Level	Total N	N w/CPM	Unadjusted model
				OR	95% CI	value
Age	Continuous	144	81	1.00	0.96–1.03	0.79
Diagnosis	Year	144	81	0.98	0.89–1.08	0.71
Race	Nonwhites	30	17	Ref		0.96
	Whites	114	64	0.98	0.44–2.20
Marital status	Married	103	54	Ref		0.14
	Other	41	27	1.75	0.83–3.71
Education	<High school	102	57	Ref		0.95
	≥ High school	29	16	0.97	0.42–2.23
Family history of breast cancer	No	72	37	Ref		0.23
	Yes	70	43	1.51	0.77–2.94
Family history of ovarian cancer	No	123	71	Ref		0.40
	Yes	19	9	0.66	0.25–1.74
Stage	I	42	24	Ref		0.25
	II	70	43	1.19	0.55–2.60
	III	32	14	0.58	0.23–1.48
Nodal status	Node 0	71	43	Ref		0.63
	Node 1	45	25	0.81	0.38–1.73
	Node 2	12	6	0.65	0.19–2.22
	Node 3	16	7	0.51	0.17–1.52
HR status	ER−/PR−	71	36	Ref		0.21
	ER+ or PR+	72	44	1.53	0.79–2.97
HER2/neu status	Negative	125	71	Ref		0.76
	Positive	17	9	0.86	0.31–2.36

HR: hormone receptor; CPM: contralateral prophylactic mastectomy; OR: odds ratio.