Survival Outcomes of Breast-Conserving Therapy versus Mastectomy in Early-Stage Breast Cancer, Including Centrally Located Breast Cancer: A SEER-Based Study
Table 7
Multivariate survival analysis of prognostic factors among BCT patients with tumor located in the central portion and other quadrants.
Cox-OS
Cox-BCSS
Fine–Gray
CS
HR
95% CI
-value
HR
95% CI
-value
HR
95% CI
-value
HR
95% CI
-value
UOBC vs. CLBC
0.932
0.869–0.999
0.047
—
—
0.319
—
—
0.578
—
—
0.482
UOBC vs. CLBC (matched)
0.851
0.773–0.938
0.001
—
—
0.136
—
—
0.410
—
—
0.290
UIBC vs. CLBC
—
—
0.715
1.210
1.071—1.366
0.002
1.221
1.079—1.381
0.002
1.214
1.075—1.371
0.002
LOBC vs. CLBC
—
—
0.992
1.161
1.022—1.319
0.022
1.170
1.02—1.333
0.018
1.162
1.023—1.321
0.021
LIBC vs. CLBC
1.135
1.04—1.233
0.003
1.360
1.194—1.550
<0.001
1.391
1.218—1.588
<0.001
1.383
1.213—1.576
<0.001
BCT, breast-conserving therapy; UOBC, upper-outer breast cancer; CLBC, centrally located breast cancer; UIBC, upper-inner breast cancer; LOBC, lower-outer breast cancer; LIBC.
