Clinical Features and Prognosis Analysis of Hormone Receptor-Positive, HER2-Negative Breast Cancer with Differential Expression Levels of Estrogen and Progesterone Receptors: A 10-Year Retrospective Study
Table 1
Tumor and patient characteristics stratified by the ER statue.
Characteristics
Total N = 283 (%)
ER >10% N = 261 (%)
1% ≤ ER < 10% N = 22 (%)
value
Age (y)
0.315
<50
134 (47.3%)
122 (46.7%)
12 (54.5%)
≥50
149 (52.7%)
139 (53.3%)
10 (45.5%)
Menstrual status
0.353
Pre/Peri-
137 (48.4%)
125 (47.9%)
12 (54.5%)
Post-
146 (51.6%)
136 (52.1%)
10 (45.5%)
Histology type
0.430
NI＆IST
37 (13.1%)
35 (13.4%)
2 (9.1%)
NST
246 (86.9%)
261 (86.6%)
20 (90.9%)
Ki-67
0.321
<14%
173 (61.1%)
158 (60.5%)
15 (68.2%)
≥14%
110 (38.9%)
103 (39.5%)
7 (31.8%)
Tumor size (cm)
0.923
T1
147 (51.9%)
136 (52.1%)
11 (50.0%)
T2
126 (44.5%)
115 (41.1%)
11 (50.0%)
T3
8 (2.8%)
8 (3.1%)
0 (0.0%)
T4
2 (0.7%)
2 (0.8%)
0 (0.0%)
ALN status
0.007
0
188 (66.4%)
175 (67.0%)
13 (59.1%)
1–3
64 (22.6)
62 (23.8%)
2 (9.1%)
≥4
31 (11.0%)
24 (9.2%)
7 (31.8%)
Stage
0.011
0–I
114 (40.3%)
105 (40.2%)
9 (40.9%)
II
133 (47.0%)
127 (48.7%)
6 (27.3%)
III
36 (12.7%)
29 (11.1%)
7 (31.8%)
Surgical procedure
0.876
BCS
27 (9.6%)
25 (9.6%)
2 (9.5%)
SM
16 (5.7%)
16 (6.1%)
0 (0.0%)
MRM
214 (75.9%)
197 (75.5%)
17 (81.0%)
ERM
25 (8.9%)
23 (8.8)%
2 (9.5%)
(NI: noninvasive breast carcinoma; IST: invasive breast carcinoma of special type; INST: invasive breast carcinoma of no special type; BCS: breast-conserving surgery; SM: simple mastectomy; MRM: modified radical mastectomy; ERM: extended radical mastectomy).
