Research Article

Clinical Features and Prognosis Analysis of Hormone Receptor-Positive, HER2-Negative Breast Cancer with Differential Expression Levels of Estrogen and Progesterone Receptors: A 10-Year Retrospective Study

Table 2

Tumor and patient characteristics stratified by ER and PR statue.

CharacteristicsTotal
N = 278 (%)
ER > 10% & PR>20%
N = 201 (%)
ER > 10%&1% ≤ PR ≤ 20% N = 60 (%)1% ≤ ER < 10%&1% ≤ PR ≤ 20%
N = 17 (%)
value

Age (y)0.011
 <50130 (46.8%)104 (51.7%)18 (30.0%)8 (47.1%)
 ≥50148 (53.2%)97 (48.3%)42 (70.0%)9 (52.9%)
Menstrual status0.001
 Pre/Peri-133 (47.8%)109 (54.2%)16 (26.7%)8 (47.1%)
 Post-145 (52.2%)92 (45.8%)44 (73.3%)9 (52.9%)
Histology type0.254
NI&IST37 (13.3%)23 (11.4%)12 (20.0%)2 (11.8%)
INST241 (86.7%)178 (88.6%)48 (80.0%)15 (88.2%)
Ki-670.308
 <14%170 (61.2%)126 (62.7%)32 (53.3%)12 (70.6%)
 ≥14%108 (38.8%)75 (37.3%)28 (46.7%)5 (29.4%)
Tumor size (cm)0.024
 T1147 (52.2%)108 (53.7%)28 (46.7%)9 (52.9%)
 T2123 (44.2%)88 (43.8%)27 (45.0%)8 (47.1%)
 T38 (2.9%)5 (2.5%)3 (5.0)0 (0.0%)
 T42 (0.7%)0 (0.0%)2 (3.3%)0 (0.0%)
ALN status0.190
 0186 (66.9%)137 (68.2%)38 (63.3%)11 (64.7%)
 1–364 (23.0%)51 (25.4%)11 (18.3%)2 (11.8%)
 ≥428 (10.1%)13 (6.5%)11 (18.3%)4 (23.5%)
Stage0.008
 0–I112 (40.3%)83 (41.3%)22 (36.7%)7 (41.2%)
 II133 (47.8%)103 (51.2%)24 (40.0%)6 (35.3%)
 III33 (11.9%)15 (7.5%)14 (23.3%)4 (23.5%)
Surgical procedure0.882
 BCS27 (9.7%)18 (9.0%)7 (11.7%)2 (11.8%)
 SM16 (5.8%)11 (5.5%)5 (8.3%)0 (0.0%)
 MRM211 (75.9%)153 (76.1%)44 (73.3%)14 (82.4%)
 ERM24 (8.6%)19 (9.5)%4 (6.7%)1 (5.9%)