The Breast Journal

Review Article

The Efficacy of Low-Kilovoltage X-Rays Intraoperative Radiation as Boost for Breast Cancer: A Systematic Review and Meta-Analysis

Table 3

Assessment of cohort studies with the Newcastle-Ottawa Scale (NOS).
StudySelectionComparabilityOutcomeQuality score
Representative treatment groupRepresentative reference groupAssignment for treatmentOutcome unpresentedAssessment of outcomeLong enough follow-upAdequate follow-up
Blank et al.★☆★★☆☆★☆★★★★★★
Wenz et al.★☆★★☆☆★☆★★★★★★
Kolburg et al.☆★★★★★★☆★★★★★★★★
Pez M et al.★☆★★☆☆★★★★★★★★★
Valente et al.★★★★★★★★★★★★★★★★★★
Chang et al.★☆★★☆☆★☆★★★★★★
Stoian et al.★☆★★☆☆★☆★★★★★★
Onthong et al.★☆★★☆☆★☆★★★★★★
Sarria et al.★☆★★☆☆★☆★★★★★★
Hochhertz et al.★☆★★☆☆★★★★★★★★★
Cho et al.★☆★★☆☆★☆★★★★★★
Comparability variables: 1 = age; 2 = tumor size; 3 = lymph node status; 4 = tumor grade; 5 = hormone receptor status; 6 = HER2 status. If all characteristics were comparable, two stars; if two or three characteristics were comparable, one star; otherwise, no star.