Research Article
Evaluating Low HER2 Status in Invasive Breast Carcinoma via HER2 Immunohistochemistry, with HER2 FISH Correlation: A Cohort of 112 Patients
Table 2
Patient demographics and tumor characteristics of different rescored subgroups.
| | | HER2
(Absent) | HER2
(Very low) | HER2
(1+) | HER2
(2+) |
| | Number of slides (n) | 15 | 35 | 63 | 1 | | Age (mean) | 65.93 | 63.71 | 67.50 | 76 | | Status (alive/deceased) (n) | 14/1 | 35/0 | 61/2 | 1/0 | | Core biopsy/excision (n) | 13/2 | 34/1 | 54/9 | 1/0 | | Type of tumor | | Ductal | 10 | 22 | 42 | 1 | | Lobular | 3 | 10 | 15 | — | | Poorly differentiated, not further categorized | 2 | 1 | 2 | — | | Ductal + lobular | — | 1 | 4 | — | | Ductal + metaplastic | — | 1 | — | — | | Tumor size (mean) | 7.85 mm | 7.73 mm | 8.81 mm | 4 mm | | Tumor grade (n) | | Grade 1 | 1 | 11 | 17 | 1 | | Grade 2 | 6 | 13 | 37 | — | | Grade 3 | 8 | 11 | 9 | — | | Hormonal status (n) | | ER+/PR+ | 6 | 25 | 56 | 1 | | ER+/PR− | 3 | 3 | 4 | — | | ER−/PR+ | 1 | 3 | 2 | — | | ER−/PR− | 5 | 4 | 1 | — |
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