The Potential Value of Near Patient Platelet Function Testing in PCI: Randomised Comparison of 600 mg versus 900 mg Clopidogrel Loading Doses

Table 3

Response to clopidogrel in PCI patients randomised to 600 mg and 900 mg loading doses. (PRU: reduction compared to baseline; %PIn: Percentage platelet inhibition due to clopidogrel; %CIn: Percentage clotting inhibition due to clopidogrel.)

	600 mg group	900 mg group	$P$ value
PRU
1 hour	$10.4\pm 10.3$	$22.3\pm 9.1$	.09
2 hour	$35.9\pm 13.3$	$44.5\pm 9.5$	.31
6 hour	$37.2\pm 15.8$	$55.3\pm 9.1$	.06
24 hour	$37.9\pm 17.0$	$60.9\pm 9.1$	.04
%PIn
1 hour	13.0 ± 7.2	22.0 ± 7.6	.10
2 hours	26.5 ± 9.5	33.2 ± 8.5	.31
6 hours	33.2 ± 8.9	45.9 ± 8.4	.06
24 hours	24.7 ± 7.1	37.8 ± 7.7	.06
%CIn
1 hour	4.0 ± 11.2	4.4 ± 12.4	.95
2 hours	19.8 ± 11.7	23.3 ± 12.1	.68
6 hours	25.8 ± 8.6	35.7 ± 8.7	.13
24 hours	18.1 ± 11.5	31.2 ± 10.2	.19