Thrombosis

Thrombosis / 2010 / Article / Tab 3

Research Article

The Potential Value of Near Patient Platelet Function Testing in PCI: Randomised Comparison of 600 mg versus 900 mg Clopidogrel Loading Doses

Table 3

Response to clopidogrel in PCI patients randomised to 600 mg and 900 mg loading doses. (PRU: reduction compared to baseline; %PIn: Percentage platelet inhibition due to clopidogrel; %CIn: Percentage clotting inhibition due to clopidogrel.)

600 mg group900 mg groupP value

PRU

1 hour10.4±10.322.3±9.1.09
2 hour35.9±13.344.5±9.5 .31
6 hour37.2±15.855.3±9.1.06
24 hour37.9±17.060.9±9.1.04

%PIn

1 hour13.0 ± 7.222.0 ± 7.6.10
2 hours26.5 ± 9.533.2 ± 8.5.31
6 hours33.2 ± 8.945.9 ± 8.4.06
24 hours24.7 ± 7.137.8 ± 7.7.06

%CIn

1 hour4.0 ± 11.24.4 ± 12.4.95
2 hours19.8 ± 11.723.3 ± 12.1.68
6 hours25.8 ± 8.635.7 ± 8.7.13
24 hours18.1 ± 11.531.2 ± 10.2.19

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