The Potential Value of Near Patient Platelet Function Testing in PCI: Randomised Comparison of 600 mg versus 900 mg Clopidogrel Loading Doses

Table 4

The percentage of “poor responders’’ to clopidogrel in PCI patients randomized to 600 mg and 900 mg clopidogrel loading doses. Poor response is defined as: PRU: <30% reduction in Accumetrics PRU from baseline; %PIn: short TEG %PIn <30%; %CIn: short TEG %CIn <30%.

	600 mg group	900 mg group	$P$ value
PRU
1 hour	77 (23/30)	67 (20/30)	.57
2 hour	40 (12/30)	27 (8/30)	.29
6 hour	41 (11/27)	12 (3/26)	.02
24 hour	41 (7/17)	15 (3/20)	.07
%PIn
1 hour	70 (21/30)	77 (23/30)	.77
2 hours	60 (18/30)	43 (13/30)	.44
6 hours	43 (12/28)	30 (10/28)	.40
24 hours	61 (11/18)	37 (7/19)	.51
%CIn
1 hour	77 (23/30)	80 (24/30)	.77
2 hours	43 (13/30)	53 (16/30)	.45
6 hours	36 (10/28)	33 (9/27)	1.00
24 hours	37 (7/19)	55 (11/20)	.34