Table of Contents
Volume 2012, Article ID 247363, 5 pages
Review Article

Thrombotic Events Associated to Aspirin Therapy

Laboratoire d’Hématologie, Université Bordeaux 2, 146 Rue Léo Saignat, 33076 Bordeaux Cedex, France

Received 15 June 2011; Accepted 14 October 2011

Academic Editor: Jeanine M. Walenga

Copyright © 2012 Christian Doutremepuich et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Acetyl salicylic acid (ASA) is widely used in clinical practice. Previous studies done in rats showed unexpected thrombotic potencies of this drug used at ultra-low doses. This review is the first report in which the effects of a wide range of ASA concentration on a microvessel model of laser-induced thrombus formation and Induced Hemorrhagic Time in animals were largely studied.