Dabigatran for Stroke Prevention in Nonvalvular Atrial Fibrillation: Answers to Challenging “Real-World” Questions

Table 2

Recommendations for the management of acute coronary syndromes in the RE-LY and RELY-ABLE studies [47].

---

(1) Dabigatran should be temporarily discontinued

(2) Aspirin, clopidogrel and glycoprotein IIb/IIIa inhibitors may be administered according to usual clinical practice

(3) Heparin can be started 12 or more hours after the last dose of dabigatran or as soon as the aPTT is <1.5 × baseline value

(4) Reperfusion with primary PCI is preferable to fibrinolysis

(5) During PCI the ACT should be measured and heparin administered as needed according to usual practice

---