Review Article
The Role of Thrombophilia in Pregnancy
Table 1
Risk of VTE in inherited thrombophilia.
| Thrombophilia | OR general population | Annual incidence of first VTE (%) | OR in pregnancy (95% CI) |
| AT deficiency | 28.2 | 1.77 | 4.69 (1.30–16.96) | Protein C deficiency | 24.1 | 1.52 | 4.76 (2.15–10.57) | Protein S deficiency | 30.6 | 1.90 | 3.19 (1.48–6.86) | Factor V Leiden | 7.5 | 0.49 | Homozygous 34.4 (9.86–120.0) Heterozygous 8.32 (5.44–12.70) | Prothrombin gene mutation | 5.2 | 0.34 | Homozygous 26.36 (1.24–559.2) Heterozygous 6.80 (2.46–19.77) |
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CI: confidence interval.
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