Clinical Evaluation of Efficacy of ^99mTC -Ethambutol in Tubercular Lesion Imaging

Table 2

Biodistribution data of ${}_{}{}^{99m}T$c-EMB in Balb/c mice. The mice were administered 40 KBq of ${}_{}{}^{99m}T$c-INH, and the radioactivity in different organs was measured at 1 hr, 4 hrs, and 24 hrs, respectively. each value is the mean ± SD of three mice and expressed as percentage administered dose per gram organ.

Organ/Tissue	1 hour	4 hours	24 hours
Blood	2.0 ± 0.03	1.3 ± 0.19	0.8 ± 0.02
Heart	0.73 ± 0.21	0.54 ± 0.07	0.36 ± 0.6
Lungs	2.1 ± 0.18	1.88 ± 0.3	1.05 ± 0.04
Liver	5.5 ± 0.5	7.0 ± 0	3.83 ± 0.21
Spleen	1.41 ± 0.09	1.78 ± 0.43	1.04 ± 0.02
Intestine	6.21 ± 0.4	6.99 ± 0.17	2.09 ± 0.03
Kidney	10.3 ± 0.42	11.35 ± 0.32	2.02 ± 0.04
Muscle	1.6 ± 0.2	1.0 ± 0.2	1.68 ± 1.1
Bone	1.08 ± 0.28	0.88 ± 1	0.64 ± 0.05
Brain	0.165 ± 0.06	0.07 ± 0.19	0.06 ± 0.2
Stomach	1.01 ± 0.31	0.8 ± 1	1.0 ± 0.3