Review Article

Tuberculosis Is Not a Risk Factor for Primary Biliary Cirrhosis: A Review of the Literature

Table 2

Major susceptibility genes associated with tuberculosis [141, 142] and primary biliary cirrhosis [133140], as reported through genome wide association studies. Note that no positive associations are significantly shared between primary biliary cirrhosis (PBC) and pulmonary tuberculosis (TB).

GenePBC TB

HLA
 DR8+
 DQB1+
 DRB1+
 DQA1+
 DQA2+
Non-HLA
 STAT4+
 SPIB+
 IRF5+
 IL12A+
 IL12RB+
 MMEL1+
 CXCR5+
 NFKB1+
 JAG1+
 DYNLRB2+
 EBF1+
 TMEFF2+
 CCL17+
 HAUS6+
 PENK+
 TXNDC4+