Profile, Outcomes, and Determinants of Unsuccessful Tuberculosis Treatment Outcomes among HIV-Infected Tuberculosis Patients in a Nigerian State

Table 1

Sociodemographic and clinical characteristics of 342 TB/HIV coinfected patients in Ebonyi State, Nigeria, stratified by tuberculosis treatment outcome.

Characteristics	Frequency; (%)	Successful outcome; (%)	Unsuccessful outcome; (%)	value
Age (years)				0.75
≤40	255 (74.6)	169 (66.3)	86 (33.7)
>40	87 (25.4)	56 (64.4)	31 (35.6)
Gender				0.50
Female	164 (48.0)	105 (64.0)	59 (36.0)
Male	178 (52.0)	120 (67.4)	58 (32.6)
Residence				0.006
Urban	233 (68.1)	83 (76.1)	26 (23.9)
Rural	109 (31.9)	142 (60.9)	91 (39.1)
Facility				<0.001
Private	251 (73.4)	181 (72.1)	70 (27.9)
Public	91 (26.6)	44 (48.4)	47 (51.6)
Type of TB				0.42
Pulmonary	331 (96.8)	219 (66.2)	122 (33.8)
Extrapulmonary	11 (3.2)	6 (54.5)	5 (45.5)
Treatment category				0.95
New	319 (93.3)	210 (65.8)	109 (34.2)
Previously treated	23 (6.7)	15 (65.0)	8 (35.0)
TB regimen received				0.11
Regimen 1	196 (57.3)	122 (62.2)	74 (37.8)
Regimen 2	146 (42.7)	103 (70.5)	43 (29.5)
Received ART				0.81
Yes	117 (34.2)	78 (66.7)	39 (33.3)
No	225 (65.8)	147 (65.3)	78 (34.7)
Received CPT				0.97
Yes	189 (55.3)	124 (65.6)	65 (34.4)
No	153 (44.7)	101 (66.0)	52 (34.0)

Regimen 1: 2RHZE/6EH; regimen 2: 2RHZE/4RH (R: rifampicin, H: isoniazid, Z: pyrazinamide, and E: ethambutol); ART: antiretroviral therapy; TB: tuberculosis; HIV: human immunodeficiency virus; CPT: cotrimoxazole preventive therapy.