Tuberculin Skin Tests versus Interferon-Gamma Release Assays in Tuberculosis Screening among Immigrant Visa Applicants

Table 4

Agreement* of TST versus QFT-G, CXR versus TST, and CXR versus QFT-G.

	TST versus QFT-G	CXR versus TST	CXR versus QFT-G
Positive/positive results; 𝑛 (%)	278 (23.9)	175 (15.0)	90 (7.7)
Negative/negative results; 𝑛 (%)	413 (35.5)	408 (35.1)	647 (55.6)
Positive/negative results; 𝑛 (%)	398 (34.2)	79 (6.8)	164 (14.1)
Negative/positive results; 𝑛 (%)	74 (6.4)	501 (43.1)	262 (22.5)
Agreement; % (95% CI)	59.4 (56.6–62.2)	50.1 (47.2–52.9)	63.4 (60.6–66.2)
Kappa coefficient; 𝜅 (95% CI)	0.24 (0.19–0.28)	0.09 (0.05–0.13)	0.058 (0.001–0.115)

CXR: chest radiographs; TST: tuberculin skin test; QFT-G: QuantiFERON-TB Gold test; 𝑛: number in subset of 𝑁; 95% CI: 95% confidence interval.
*Agreement was assessed among 1,163 subjects; data from 83 subjects with indeterminate QFT-G results were excluded from analysis.