Tuberculosis Research and Treatment / 2014 / Article / Tab 1

Clinical Study

Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients

Table 1

Incidence, onset time, and seriousness of anti-TB adverse drug reactions.

Type of ADRsMinor ADRs (%)Major ADRs (%)Mean of onset time (range) days

Gastrointestinal disorders114 (91.9)10 (8.1)19 (4–57)
Liver dysfunction162 (80.6)39 (19.4)17 (12–68)
Allergic reactions63 (73.3)23 (26.7)20 (6–45)
Flu-like reactions76 (100)05 (1–9)
Arthralgia29 (85.3)5 (14.7)36 (23–55)
Hematologic disorders3 (42.8)4 (57.2)52 (29–81)
Peripheral neuropathy14 (81.4)3 (17.6)48 (38–74)
Renal impairment1 (20)4 (80)32 (27–41)
Visual impairment1 (16.7)5 (83.3)46 (34–72)
Ototoxicity1 (14.3)6 (85.7)33 (20–54)

Total464 (82.4)99 (17.6)19 (4–81)

It was from initiation of treatment. (It was the time that ADRs were found, not the exact time it happened.)