Research Article
Pharmacovigilance and Moroccan Tuberculosis Public Program: Current Situation
Table 3
Comparison of ADRs types before and after integration of PV-MTCP.
| | System Organ Class (disorders) | Period 1
(%) | Period 2
(%) | |
| | Skin and appendages disorders | 86 (26.3) | 145 (24.2) | NS | | Gastrointestinal system disorders | 29 (8.9) | 126 (21) | 0,007 | | Liver and biliary system disorders | 107 (32.8) | 87 (14.5) | NS | | General disorders | 12 (3.7) | 86 (14.4) | 0,0007 | | Central and peripheral nervous system | 42 (12.9) | 46 (7.7) | NS | | Musculoskeletal system disorders | 8 (2.4) | 36 (6) | 0,03 | | Psychiatric disorders | 6 (1.8) | 20 (3.4) | 0,04 | | Hearing and vestibular disorders | 0 | 10 (1.7) | — | | Respiratory system disorders | 0 | 10 (1.7) | — | | Metabolic disorders | 21 (6.4) | 9 (1.5) | 0,02 | | Platelet, bleeding, and clotting disorders | 5 (1.5) | 6 (1) | NS | | Endocrine disorders | 0 | 6 (1) | — | | Vision disorders | 0 | 5 (0.8) | — | | Heart rate and rhythm disorders | 2 (0.6) | 3 (0.5) | NS | | White cell disorders | 2 (0.6) | 2 (0.3) | NS | | Red blood cell disorders | 2 (0.6) | 1 (0.1) | NS | | Urinary system disorders | 5 (1.5) | 1 (0.1) | NS | | Reproductive disorders | 0 | 1 (0.1) | — |
| | Total | 327 (100) | 600 (100) | |
|
|
NS: not significant.
|
