Research Article
Association of Genetic Polymorphisms of IFNGR1 with the Risk of Pulmonary Tuberculosis in Zahedan, Southeast Iran
Table 2
Frequency distribution of INFGR1 gene polymorphisms in PTB and control subjects.
| | Gene polymorphisms | PTB
(%) | Controls
(%) | OR (95% CI) | |
| rs1327474
(−611 A/G) | | | | | | AA | 56 (32.4) | 63 (38.4) | 1.00 | — | | AG | 105 (60.7) | 94 (57.3) | 1.26 (0.79–1.98) | 0.354 | | GG | 12 (6.9) | 7 (4.3) | 1.93 (0.71–5.24) | 0.223 | | Allele | | | | | | A | 217 (62.7) | 220 (67.1) | 1.00 | — | | G | 129 (37.3) | 108 (32.9) | 1.21 (0.88–1.66) | 0.258 | rs11914
(+189 T/G) | | | | | | TT | 148 (85.5) | 112 (68.3) | 1.0 | — | | TG | 25 (14.5) | 52 (31.7) | 0.36 (0.21–0.62) | 0.0002 | | GG | 0 (0.0) | 0 (0.0) | — | — | | Allele | | | | | | T | 321 (92.8) | 276 (84.1) | 1.00 | — | | G | 25 (7.2) | 52 (15.9) | 0.41 (0.25–0.68) | 0.0006 | rs7749390
(+95 C/T) | | | | | | CC | 48 (27.7) | 34 (20.7) | 1.00 | — | | CT | 63 (36.4) | 81 (49.4) | 0.55 (0.32–0.95) | 0.038 | | TT | 62 (35.8) | 49 (29.9) | 0.88 (0.49–1.57) | 0.768 | | Allele | | | | | | C | 159 (45.9) | 149 (45.4) | 1.00 | — | | T | 187 (54.1) | 179 (54.6) | 0.98 (0.72–1.33) | 0.938 | | rs137854905 (27-bp I/D) | | | | | | DD | 173 (100) | 164 (100) | — | — | | ID | 0 (0.0) | 0 (0.0) | — | — | | II | 0 (0.0) | 0 (0.0) | — | — | | Allele | | | | | | D | 346 (100) | 328 (100) | — | — | | I | 0 (0.0) | 0 (0.0) | — | — |
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