Table of Contents Author Guidelines Submit a Manuscript
Tuberculosis Research and Treatment
Volume 2015 (2015), Article ID 561490, 6 pages
http://dx.doi.org/10.1155/2015/561490
Research Article

Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients

1Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, 5021 Bergen, Norway
2Department of Thoracic Medicine, Haukeland University Hospital, 5021 Bergen, Norway
3Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, 5021 Bergen, Norway
4National Institute for Medical Research, Muhimbili, Tanzania
5The Gade Research Group for Infection and Immunity, Department of Clinical Science, University of Bergen, 5021 Bergen, Norway

Received 31 December 2014; Revised 2 April 2015; Accepted 13 April 2015

Academic Editor: Paul R. Klatser

Copyright © 2015 Tehmina Mustafa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. C. Dandapat, B. M. Mishra, S. P. Dash, and P. K. Kar, “Peripheral lymph node tuberculosis: a review of 80 cases,” British Journal of Surgery, vol. 77, no. 8, pp. 911–912, 1990. View at Publisher · View at Google Scholar · View at Scopus
  2. M. R. Purohit, T. Mustafa, O. Mørkve, and L. Sviland, “Gender differences in the clinical diagnosis of tuberculous lymphadenitis-a hospital-based study from Central India,” International Journal of Infectious Diseases, vol. 13, no. 5, pp. 600–605, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. E. D. Carrol, J. E. Clark, and A. J. Cant, “Non-pulmonary tuberculosis,” Paediatric Respiratory Reviews, vol. 2, no. 2, pp. 113–119, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Polesky, W. Grove, and G. Bhatia, “Peripheral tuberculous lymphadenitis: epidemiology, diagnosis, treatment, and outcome,” Medicine, vol. 84, no. 6, pp. 350–362, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. M. P. Etna, E. Giacomini, M. Severa, and E. M. Coccia, “Pro- and anti-inflammatory cytokines in tuberculosis: a two-edged sword in TB pathogenesis,” Seminars in Immunology, vol. 26, no. 6, pp. 543–551, 2014. View at Publisher · View at Google Scholar
  6. J. M. Tufariello, J. Chan, and J. L. Flynn, “Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection,” Lancet Infectious Diseases, vol. 3, no. 9, pp. 578–590, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. R. Hussain, Z. Toossi, R. Hasan, B. Jamil, G. Dawood, and J. J. Ellner, “Immune response profile in patients with active tuberculosis in a BCG vaccinated area,” Southeast Asian Journal of Tropical Medicine and Public Health, vol. 28, no. 4, pp. 764–773, 1997. View at Google Scholar · View at Scopus
  8. M. L. Wilsher, C. Hagan, R. Prestidge, A. U. Wells, and G. Murison, “Human in vitro immune responses to Mycobacterium tuberculosis,” Tubercle and Lung Disease, vol. 79, no. 6, pp. 371–377, 1999. View at Publisher · View at Google Scholar · View at Scopus
  9. C. Munoz, J. Carlet, C. Fitting, B. Misset, J.-P. Bleriot, and J.-M. Cavaillon, “Dysregulation of in vitro cytokine production by monocytes during sepsis,” The Journal of Clinical Investigation, vol. 88, no. 5, pp. 1747–1754, 1991. View at Publisher · View at Google Scholar · View at Scopus
  10. S. G. M. Mfinanga, O. Morkve, R. R. Kazwala et al., “Mycobacterial adenitis: role of Mycobacterium bovis, non-tuberculous mycobacteria, HIV infection, and risk factors in Arusha, Tanzania,” East African Medical Journal, vol. 81, no. 4, pp. 171–178, 2004. View at Google Scholar · View at Scopus
  11. D. o. P. M. Ministry of Health, National Tuberculosis, and Leprosy Control Program, Tanzania, Annual Reports 1979–2001, Ministry of Health, D. o. P. M., 2005.
  12. S. Aboud, E. F. Lyamuya, E. K. Kristoffersen, and R. Matre, “Immunity to tetanus in male adults in Dar es Salaam, Tanzania,” East African Medical Journal, vol. 79, no. 2, pp. 73–76, 2002. View at Google Scholar · View at Scopus
  13. T. Mustafa, G. Bjune, R. Jonsson, R. H. Pando, and R. Nilsen, “Increased expression of fas ligand in human tuberculosis and leprosy lesions: a potential novel mechanism of immune evasion in mycobacterial infection,” Scandinavian Journal of Immunology, vol. 54, no. 6, pp. 630–639, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. T. Mustafa, S. J. Mogga, S. G. Mfinanga, O. Mørkve, and L. Sviland, “Immunohistochemical analysis of cytokines and apoptosis in tuberculous lymphadenitis,” Immunology, vol. 117, no. 4, pp. 454–462, 2006. View at Publisher · View at Google Scholar
  15. T. Mustafa, H. G. Wiker, O. Mørkve, and L. Sviland, “Reduced apoptosis and increased inflammatory cytokines in granulomas caused by tuberculous compared to non-tuberculous mycobacteria: role of MPT64 antigen in apoptosis and immune response,” Clinical and Experimental Immunology, vol. 150, no. 1, pp. 105–113, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Denis and E. Ghadirian, “Granulocyte-macrophage colony-stimulating factor restricts growth of tubercle bacilli in human macrophages,” Immunology Letters, vol. 24, no. 3, pp. 203–206, 1990. View at Publisher · View at Google Scholar · View at Scopus
  17. V. Kindler, A.-P. Sappino, G. E. Grau, P.-F. Piguet, and P. Vassalli, “The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection,” Cell, vol. 56, no. 5, pp. 731–740, 1989. View at Publisher · View at Google Scholar · View at Scopus
  18. N. O. Nielsen, B. Soborg, M. Børresen, M. Andersson, and A. Koch, “Cytokine responses in relation to age, gender, body mass index, Mycobacterium tuberculosis infection, and otitis media among inuit in greenland,” American Journal of Human Biology, vol. 25, no. 1, pp. 20–28, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. G. H. Bothamley, “Sex and gender in the pathogenesis of infectious tuberculosis: a perspective from immunology, microbiology and human genetic,” in Gender and Tuberculosis, V. K. T. A. W. A. Diwan, Ed., NHV Report, pp. 41–53, The Nordic School of Public Health, Gothenburg, Sweden, 1998. View at Google Scholar
  20. M. A. Hoeve, N. D. L. Savage, T. de Boer et al., “Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells,” European Journal of Immunology, vol. 36, no. 3, pp. 661–670, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Cruz, A. G. Fraga, J. J. Fountain et al., “Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis,” The Journal of Experimental Medicine, vol. 207, no. 8, pp. 1609–1616, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. S. A. Khader, G. K. Bell, J. E. Pearl et al., “IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge,” Nature Immunology, vol. 8, no. 4, pp. 369–377, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Korn, E. Bettelli, M. Oukka, and V. K. Kuchroo, “IL-17 and Th17 cells,” Annual Review of Immunology, vol. 27, pp. 485–517, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. N. N. Sotiriadou, S. A. Perez, A. D. Gritzapis et al., “Beneficial effect of short-term exposure of human NK cells to IL15/IL12 and IL15/IL18 on cell apoptosis and function,” Cellular Immunology, vol. 234, no. 1, pp. 67–75, 2005. View at Publisher · View at Google Scholar · View at Scopus