Phenotypic and Genotypic Analysis of Multidrug-Resistant Mycobacterium tuberculosis Isolates from Sudanese Patients

Table 2

Explaining the position and frequency of polymorphism with resistance pattern of isolates.

Mutation position	Polymorphism	Frequency (%)	Resistance pattern
			RIF	INH	STM	EMB
222	C → A	23%	R	R	R	S
			S	S	R	S
			R	S	R	S
885	G → T	8%	S	S	R	S
892	G → A	31%	S	R	R	S
			S	S	R	S
			R	R	R	S
			R	R	R	R
904	A → G	15%	S	R	R	S
			R	R	R	R
906	A → G	8%	S	R	R	S
	T → A	8%	R	S	R	S
1400	G → A	8%	R	R	R	R
	G → C	8%	S	S	R	S

R: resistance; S: sensitive; RIF: rifampicin; INH: isoniazid; STM: streptomycin; EMB: ethambutol.