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Tuberculosis Research and Treatment
Volume 2018, Article ID 4287842, 7 pages
Research Article

An Evaluation of Treatment Outcomes in a Cohort of Clients on the DOTS Strategy, 2012–2016

1Laboratory Department, Metropolitan Hospital, P.O. Box 174, Cape Coast, Ghana
2Department of Community Medicine and Health, Anglican University College of Technology, P.O. Box 74, Nkoranza, Ghana
3Noguchi Memorial Institute for Medical Research, Department of Parasitology, College of Health Sciences, University of Ghana, Legon, Accra, Ghana
4Department of Animal Biology and Conservation Sciences, University of Ghana, Legon, Accra, Ghana

Correspondence should be addressed to Ato Kwamena Tetteh; moc.kooltuo@hettetka

Received 16 October 2017; Accepted 18 January 2018; Published 15 February 2018

Academic Editor: William N. Rom

Copyright © 2018 Ato Kwamena Tetteh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present, for the first time, an evaluation of treatment outcomes in a cohort at a TB referral centre in the Central Region of Ghana. Of the 213 clients placed on DOTS, 59.2% (126/213) were sputum smear-positive. An overall cure rate of 90.2% (51.6% cured + 37.6% completed) and a death rate of 8.5% (18/213) were estimated. Of the number of clients who died, 5.7% (12/213) were males (χ2 = 2.891, ; LR = 3.004, ). Deaths were only recorded among clients who were > 19 years old (χ2 = 40.319, ; LR = 41.244, ). Also, 0.9% (2/213) was lost to follow-up, while 1.4% (3/213) had treatment failure. In total, 13.6% (7.0%, 15/213 males, and 6.6%, 14/213 females) of clients who were placed on DOTS were HIV seropositive. Ages of 40–49 years had the highest number, 13/213 (6.1%), infected with HIV, though the difference among the remaining age groups was not statistically significant (χ2 = 9.621, ). Furthermore, 7.0% (15/213) had TB/HIV coinfection. Out of them, 9 were cured and 5 died at home, while 1 had treatment failure. Tuberculosis/HIV infection prevention advocacy and interventions that address sociodemographic determinants of unfavourable treatment outcomes are urgently required to augment national efforts towards control.