Mycobacterial Lineages Associated with Drug Resistance in Patients with Extrapulmonary Tuberculosis in Addis Ababa, Ethiopia

Table 2

Distribution of first-line drug-resistance with Mycobacterium tuberculosis complex lineages and families among extrapulmonary TB ().

Lineages (Ls) ()	Sublineages	Resistance (%)
		STR	INH	RIF	EMB	PZA	MDR-TB
Euro-American (L4) (111)		5 (4.5)	14 (12.6)	8 (7.2)	2 (1.8)	14 (12.6)	8 (7.2)
	T	1 (0.9)	2 (1.8)	0	1 (0.9)	2 (1.8)	0
	T3-ETH	3 (2.7)	10 (9.0)	7 (6.3)	1 (0.9)	0	7 (6.3)
	Haarlem	1 (0.9)	1 (0.9)	1 (0.9)	0	3 (2.7)	1 (0.9)
	X1	0	0	0	0	0	0
	LAM	0	1 (0.9)	0	0	2 (1.8)	0
	Ural	0	0	0	0	1 (0.9)	0
East-African-Indian (L3) [26]	CAS	3 (11.5)	5 (19.2)	4 (15.4)	0	6 (23.1)	4 (15.4)
Indo-Oceanic (L1) [1]	EAI5	1 (100)	1 (100)	1 (100)	0	0	1 (100)
East-Asian (L2) [1]	Beijing	0	0	0	0	0	0
Bovis [3]	BOV	0	1 (33.3)	0	0	1 (33.3)	0
Unknown strain [9]	Not defined	0	1 (11.1)	1 (11.1)	1 (11.0)	1 (11.1)	1 (11.1)

EA: Euro-American; EAI: East-African-Indian; IO: Indo-Oceanic; EAI: East-African-Indian; CAS: Central Asian Strain; H: Harlem; BOV: Bovis; LAM: Latin American Mediterranean; ETH: Ethiopia; L: lineages; STM: streptomycin; INH: isoniazid; RIF: rifampicin; EMB: ethambutol; PZA: pyrazinamide; MDR: multidrug resistance.