Tuberculosis Drug Susceptibility, Treatment, and Outcomes for Belarusian HIV-Positive Patients with Tuberculosis: Results from a National and International Laboratory

Table 1

Definitions for anti-TB drug resistance [29, 30].

Resistance terminology	Definition
Drug-sensitive TB (DS-TB)	Mtb sensitive to all first-line anti-TB drugs
Monoresistant TB	Mtb resistant to one first-line anti-TB drug only
Drug-resistant TB (DR-TB)	At least MDR-TB, combined terminology for any of the below definitions
Multidrug-resistant TB (MDR-TB)	Mtb resistant to at least both isoniazid and rifampicin
Preextensive drug-resistant TB (preXDR-TB)	Mtb resistant to isoniazid and rifampicin and either any fluoroquinolone or a second-line injectable agent but not both
Extensive drug-resistant TB (XDR-TB)	Mtb resistant to isoniazid and rifampicin and to any fluoroquinolone and to at least one of three second-line injectable drugs (capreomycin, kanamycin, and amikacin)

Mtb = Mycobacterium tuberculosis.