Comparison of Interferon-Gamma Release Assay and Tuberculin Skin Test for the Screening of Latent Tuberculosis in Inflammatory Bowel Disease Patients: Indian Scenario

Table 7

Comparison of various studies upon the prevalence of LTBI in IBD patients.

Study	Country	No. of patients ()	Control ()	Male (%)	Mean age (yrs)	IBD UC/CD	BCG (%)	TST+ve (%)	IGRA +ve (%)	IGRA method	Indeterminant IGRA (%)	Kappa (κ) concordance/agreement TST/IGRA
Papay et al., 2011 [21]	Austria	208	—	49	36	152/56	—	12.5	7.2	QFT-GIT	7.7	0.21
Schoepfer et al., 2008 [12]	Switzerland	212	44	49	31	44/114	70	18	8.3	QFT-GIT	3	0.029
Andrisani et al., 2013 [15]	Italy	92	50	39.6		60/32	—	15.2	14.1	QFT-TST	0.9	0.51
Arias-Guillen et al., 2014 [25]	Spain	205	—	50	44	157/48	—	26.8	7.8	QFT-GIT, TSPOT	8.4	0.34
Wong et al., 2014 [20]	China	268	234	160	43	128/136	95	9.9	20.6	QFT-GIT	4	0.19
Kurti et al., 2015 [26]	Hungary	166	—	54	24	122/44	—	21	8.4	QFT-GIT	0.6	0.41
Abreu et al., 2016 [27]	Portugal	250	—	44	36	81/19	—	23	10	QFT-GIT	2.2	0.22
Our study	India	131IBD	126	60	40.1	121/10	26	23.3	18.9	QFT-GIT	4.3	0.66