Treatment Outcomes and Associated Factors in Tuberculosis Patients at Atwima Nwabiagya District, Ashanti Region, Ghana: A Ten-Year Retrospective Study

Table 2

TB treatment regimen.

Patient category	Definition	Initial phase treatment	Continuous phase treatment
		Daily (28 doses/month)	Daily (28 doses/month)
All new clients	New smear-positive	of HRZE	doses of HR
	New smear-negative pulmonary TB
	Concomitant HIV disease
	Extrapulmonary TB
Previously treated sputum smear-positive pulmonary TB	Relapse		doses of HRE
	Treatment after interruption
	Treatment failure
Childrenª	Children below 12 years	doses of HRZ	doses of HR

Direct observation of treatment intake is required and always in regimen including rifampicin. ^¥Streptomycin may be used instead of ethambutol. In meningitis, ethambutol should be replaced by streptomycin. ªIn children with meningitis, add streptomycin in the initial phase. Codes for Tb drugs: H: isoniazid; R: rifampicin; Z: pyrazinamide; S: streptomycin; E: ethambutol. Fixed drug combinations (FDC) codes: (HR): isoniazid + rifampicin; (HRZ): isoniazid + rifampicin + pyrazinamide; (HRZE): isoniazid + rifampicin + pyrazinamide + ethambutol.