Research Article
The Burden of Bacteriologically Negative TB Diagnosis: A Four-Year Review of Tuberculosis Cases at a Tertiary Facility
Table 1
Demographic and clinical characteristics of the study population.
| | Parameters | Study population
(%) | Treatment completed
(%) | Lost to follow-up
(%) | Died
(%) | Treatment failure
(%) | Treatment stopped
(%) | Transferred out
(%) | value |
| | Total sample | 1933 | 752 (38.9) | 167 (8.6) | 483 (25.0) | 7 (0.4) | 30 (1.6) | 494 (25.6) | |
| | Age group in years | | 13–24 | 268 (13.9) | 91 (12.1) | 23 (13.8) | 78 (16.2) | 0 (0.0) | 3 (10.0) | 73 (14.8) | 0.524 | | 25–44 | 890 (46.1) | 370 (49.2) | 75 (44.9) | 217 (44.9) | 3 (42.9) | 12 (40.0) | 213 (43.1) | | 45–64 | 606 (31.4) | 228 (30.3) | 57 (34.1) | 152 (31.5) | 3 (42.9) | 12 (40.0) | 154 (31.2) | | ≥65 | 167 (8.7) | 63 (8.4) | 12 (7.2) | 36 (7.5) | 1 (14.3) | 3 (10.0) | 52 (10.5) |
| | Gender | | | | | | | | | | Female | 706 (36.5) | 264 (35.1) | 64 (38.3) | 186 (38.5) | 2 (28.6) | 8 (26.7) | 182 (36.8) | 0.673 | | Male | 1,227 (63.5) | 488 (64.9) | 103 (61.7) | 297 (61.5) | 5 (71.4) | 22 (73.3) | 312 (63.2) |
| | Patient type | | New | 1,818 (94.1) | 698 (92.8) | 157 (94.0) | 458 (94.8) | 5 (71.4) | 29 (96.7) | 471 (95.3) | 0.382 | | Retreatment | 110 (5.7) | 52 (6.9) | 10 (6.0) | 24 (4.8) | 2 (28.6) | 1 (4.5) | 21 (4.3) | | Not known | 5 (0.3) | 2 (0.3) | 0 (0.0) | 1 (0.2) | 0 (0.0) | 0 (0.0) | 2 (0.4) |
| | Disease classification | | Pulmonary | 986 (51.0) | 424 (56.4) | 88 (52.8) | 255 (52.8) | 5 (71.4) | 14 (46.7) | 200 (40.5) | <0.001 | | Extrapulmonary | 935 (48.4) | 322 (42.8) | 78 (46.7) | 225 (46.6) | 2 (28.6) | 16 (53.3) | 292 (59.1) | | Not known | 12 (0.6) | 6 (0.8) | 1 (0.6) | 3 (0.6) | 0 (0.0) | 0 (0.0) | 2 (0.1) |
| | Bacteriological confirmation | | Confirmed | 606 (31.4) | 289 (38.4) | 58 (34.7) | 146 (30.2) | 5 (71.4) | 0 (0.0) | 108 (21.9) | <0.001 | | Unconfirmed | 1189 (61.5) | 415 (55.2) | 102 (61.1) | 300 (62.1) | 2 (28.6) | 28 (93.3) | 342 (69.2) | | No documentation | 138 (7.1) | 48 (6.4) | 7 (4.2) | 37 (7.7) | 0 (0.0) | 2 (6.7) | 44 (8.9) |
| | Radiological report | | Suggestive | 1,593 (82.4) | 628 (83.5) | 140 (83.8) | 397 (82.2) | 5 (71.4) | 24 (80.0) | 399 (80.8) | 0.202 | | Not suggestive | 140 (7.2) | 51 (6.8) | 12 (7.2) | 38 (7.9) | 0 (0.0) | 2 (6.7) | 37 (7.5) | | Not done | 102 (5.3) | 32 (4.3) | 6 (3.6) | 26 (5.4) | 0 (0.0) | 1 (3.3) | 37 (7.5) | | Not known | 98 (5.1) | 41 (5.5) | 9 (5.4) | 22 (4.6) | 2 (28.6) | 3 (10.0) | 21 (4.3) |
| | HIV status | | Positive | 576 (29.8) | 172 (22.9) | 42 (25.2) | 218 (45.1) | 1 (14.3) | 3 (10.0) | 140 (28.3) | <0.001 | | Negative | 1,096 (56.7) | 499 (66.4) | 102 (61.1) | 191 (39.5) | 6 (85.7) | 22 (73.3) | 276 (55.9) | | HIV test declined | 261 (13.5) | 81 (10.8) | 23 (13.8) | 74 (15.3) | 0 (0.0) | 5 (16.7) | nn (15.8) |
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