Research Article

In-Hospital Nonvariceal Upper Gastrointestinal Bleeding following Cardiac Surgery: Patient Characteristics, Endoscopic Lesions and Prognosis

Table 1

Patient characteristics.

No mortality,
𝑁 = 1 0 6
Mortality,
𝑁 = 2 5
𝑃 values

Age 6 8 . 7 ± 9 . 7 6 9 . 1 ± 1 2 . 3 𝑃 = 0 . 5 8 0 0
Gender (male)71.7% (63.0%–80.4%)60.0% (39.4%–80.6%) 𝑃 = 0 . 2 5 3 3
Parsonnet score24.0% (21.1%–26.8%)27.6% (21.4%–33.7%) 𝑃 = 0 . 2 7 1 7
Documented history of:
 Liver failure 1.9% (0.0%–4.5%)0.0% 𝑃 = 0 . 4 8 8 9
 Chronic renal failure13.3% (6.7%–19.9%)36.0% (15.8%–56.2%) 𝑃 = 0 . 0 0 7 6
 Heart failure13.2% (6.7%–19.8%)32.0% (12.3%–51.7%) 𝑃 = 0 . 0 2 3 8
 Ischemic heart disease76.4% (68.2%–84.6%)68.0% (48.3%–87.7%) 𝑃 = 0 . 3 8 3 3
 Other heart disease16.0% (8.9%–23.1%)12.0% (0.0%–25.7%) 𝑃 = 0 . 6 1 3 6
 Asthma5.6% (1.2%–10.1%)12.0% (0.0%–25.7%) 𝑃 = 0 . 2 5 9 6
 COPD9.4% (3.8%–15.1%)20.0% (3.2%–36.9%) 𝑃 = 0 . 1 3 5 6
 Diabetes mellitus26.4% (17.9%–35.0%)28.0% (9.1%–46.9%) 𝑃 = 0 . 8 7 2 0
 Major recent operation0.9% (0.0%–2.8%)0.0% (0.0%-0.0%) 𝑃 = 0 . 6 2 5 9
 Major sepsis0.0%0.0%
 Disseminated malignancy0.0%0.0%
 Other solid malignancy8.5% (3.1%–13.9%)0.0% (0.0%-0.0%) 𝑃 = 0 . 1 3 1 1
 Hematological malignancy1.0% (0.0%–2.8%)0.0% (0.0%-0.0%) 𝑃 = 0 . 6 2 4 2
 Dementia0.0%0.0%
 CVA/TIA10.4% (4.5%–16.3%)16.0% (0.6%–31.4%) 𝑃 = 0 . 4 2 7 1
 Hypertension67.9% (58.9%–77.0%)72.0% (53.1%–90.9%) 𝑃 = 0 . 6 9 2 6
 Trauma1.9% (0.0%–4.5%)4.0% (0.0%–12.3%) 𝑃 = 0 . 5 2 5 2
Symptoms on presentation:
 Melena59.2% (49.6%–68.9%)60.0% (39.4%–80.6%) 𝑃 = 0 . 9 4 3 5
 Coffee ground emesis25.0% (16.5%–33.5%)68.0% (9.1%–46.9%) 𝑃 = 0 . 7 5 7 6
 Hematochezia13.5% (6.8%–20.1%)12.0% (0.00%–25.7%) 𝑃 = 0 . 8 4 6 2
 Hematemesis11.5% (5.3%–17.8%)12.0% (0.00%–25.7%) 𝑃 = 0 . 9 4 8 5
 Initial hemodynamic instability45.8% (35.7%–56.0%)52.2% (30.1%–74.3%) 𝑃 = 0 . 5 8 4 2
Medication during hospitalization:
 PPI10.9% (4.7%–17.1%)13.0% (0.0%–27.9%) 𝑃 = 0 . 7 6 8 5
 H2RA29.7% (20.6%–38.8%)13.0% (0.0%–27.9%) 𝑃 = 0 . 1 0 2 8
 Steroids15.1% (8.2%–22.0%)28.0% (9.1%–46.9%) 𝑃 = 0 . 1 2 7 1
 Aprotinin0.0%0.0%
 ASA88.6% (82.4%–94.8%)88.0% (74.3%–100.0%) 𝑃 = 0 . 9 3 5 9
 Heparin95.3% (91.2%–99.4%)96.0% (87.7%–100.0%) 𝑃 = 0 . 8 7 7 4
 Coumadin45.3% (35.7%–54.9%)60.0% (39.4%–80.6%) 𝑃 = 0 . 1 8 5 2
 Clopidogrel22.6% (14.5%–30.7%)24.0% (6.0%–42.0%) 𝑃 = 0 . 8 8 4
 LMWH6.6% (1.8%–11.4%)8.0% (0.0%–19.4%) 𝑃 = 0 . 8 0 3 9
 NSAIDS42.5% (32.9%–52.0%) 40.0% (19.4%–60.6%) 𝑃 = 0 . 8 2 3 1
 Steroids15.1% (8.2%–22.0%)28.0% (9.1%–46.9%) 𝑃 = 0 . 1 2 7 1